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周期素依赖性激酶11抗体
产物名称 | 英文名称 | 货号 |
周期素依赖性激酶11抗体 | CDK11 | GOY-01K0148 |
商品属性：
英文名称: CDK11
中文名:周期素依赖性激酶11抗体
别 名；Galactosyltransferase
associated protein kinase p58/GTA; CD11B_HUMAN; CDK11B; CDC2L1; PITSLREA; PK58;
CDK11-p110; CDK11-p46; CDK11-p58; CDK11; CDK11 p110; CDK11 p46; CDK11 p58;
CLK-1; p58; p58CDC2L1; p58CLK-1; p58 CLK-1; PK58; Cyclin-dependent kinase 11B;
Cell division cycle 2-like protein kinase 1; Cell division protein kinase 11B;
Galactosyltransferase-associated protein kinase p58/GTA; PITSLRE
serine/threonine-protein kinase CDC2L1.
研究领域；肿瘤 细胞生物 免疫学 转录调节因子 激酶和磷酸酶
抗体来源；Rabbit
克隆类型；Polyclonal
交叉反应；(predicted:
Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep, )
产物应用；WB=1:500-2000
ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in
other applications.
optimal
dilutions/concentrations should be determined by the end user.
理论分子量；93kDa
细胞定位；细胞核
性 状；Liquid
浓 度；1mg/ml
免 疫 原；KLH
conjugated synthetic peptide derived from human CDK11: 21-120/795
亚 型；IgG
纯化方法；affinity
purified by Protein A
保存条件；Shipped at
4℃. Store at -20 °C for one
year. Avoid repeated freeze/thaw cycles.
注意事项；This
product as supplied is intended for research use only, not for use in human,
therapeutic or diagnostic applications.
产物介绍:
Summary: This gene encodes a member of the p34Cdc2
protein kinase family. p34Cdc2 kinase family members are known to be
essential for eukaryotic cell cycle control. This gene is in close proximity
to CDC2L2, a nearly identical gene in the same chromosomal region. The gene
loci including this gene, CDC2L2, as well as metalloprotease MMP21/22,
consist of two identical, tandemly linked genomic regions which are thought
to be a part of the larger region that has been duplicated. This gene and
CDC2L2 were shown to be deleted or altered frequently in neuroblastoma with
amplified MYCN genes. The protein kinase encoded by this gene could be
cleaved by caspases and was demonstrated to play roles in cell apoptosis.
Several alternatively spliced variants of this gene have been reported.
[provided by RefSeq, Jul 2008]. Function: Appears to play multiple roles in cell cycle
progression, cytokinesis and apoptosis. The p110 isoforms have been suggested
to be involved in pre-mRNA splicing, potentially by phosphorylating the
splicing protein SFRS7. The p58 isoform may act as a negative regulator of
normal cell cycle progression. |
多克隆抗体制备：
我公司合成抗原，保证阳性血清和抗体贰尝滨厂础效价达到1：32000，由蛋白抗原制备的多抗，保证奥叠检测结果是阳性。技术服务实行分步报价，按节点收费，为客户节约成本。
鼠单克隆抗体制备:
客户可根据项目实际需求情况灵活选择进行，我公司将为您的项目提供专业的建议。在制备过程中，与客户互动验证，确保最终制备的抗体贰尝滨厂础阳性血清检测达到合同要求的同时，也能满足客户抗体最终应用验证需求。技术服务实行分步报价，按节点收费，为客户节约成本。
重组抗体表达服务:
重组抗体技术使制备人源化抗体和人源抗体成为可能，而这是其他常规的多克隆或单克隆抗体制备方法无法做到的。我公司已搭建好的抗体测序、重组抗体表达等先进平台，能为客户提供各种类型的重组抗体表达服务，包含鼠源单克隆抗体构建及表达、更换恒定区亚型的嵌合抗体表达，抗体人源化改造及表达等服务。
单项免疫学及检测服务:
我公司也为客户提供单项免疫学和检测服务，如动物免疫、动物饲养、抗体修饰服务（如贵滨罢颁，贬搁笔等的标记）、以及贰尝滨厂础，奥叠，滨贬颁，顿叠等检测服务。
抗体定制服务:
已注册商标，主要用于抗体药物发现和开发，是我公司针对有特定应用要求和各种模型测试的客户量身定制的专业服务，主要面向工业客户。
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